The fresh take to proportions of these analyses was not place good priori, and only the new offered data from for every data were utilized.
Diligent features and you can version as we grow older
Desk 1 refers to the latest standard characteristics of one’s 6442 people assessed (Extra file 1: Desk S1 brings this type of research for every single studies). Complete, a little less than one to-1 / 2 of the fresh new people was basically people thaifriendly, although this ratio enhanced that have increasing years. The fresh mean (SD) period of clients is 63.2 (ten.9) many years, in addition to their anthropometric tips indicated that 46.5% were in the variety of carrying excess fat [complete suggest (SD) BMI: 30.step 3 (5.2) kg/meters 2 ], predominantly of main variety of (mean hips circumference, all: 101.8 cm; women: 99.5 cm, men: 103.seven cm). Brand new indicate (SD) lifetime of T2D is eight.cuatro (6.7) many years, and more than ninety% out of clients was indeed searching oral antidiabetes medications; the remainder try getting life change pointers only. Indicate FBG and you can, including, suggest HbA1c was above ancient non-customized necessary targets (suggest FBG: nine.0 mmol/L; mean HbA1c: seven.4%). Besides HDL-C, SBP, and you can DBP, imply philosophy of your leftover classical cardio exposure issues (LDL-C and triglycerides) have been a lot more than their recommended thresholds. These types of thresholds was described in the Profile 1.
Classic cardiovascular exposure affairs or any other diligent characteristics stratified by the decades, Body mass index, and you will HbA1c ranges. Beliefs is means and you will 95% rely on times, determined into the conveyed strata of the founded variables (years, Bmi, and you may HbA1c). This new straight dotted traces in certain maps show address viewpoints required of the American Diabetic issues Relationship . Famous people = age; Triangles = BMI; Groups = HbA1c. Abbreviations: Bmi, body mass index; DBP, diastolic blood pressure levels; FBG, accelerated blood glucose levels; HbA1c, glycosylated hemoglobin; HDL, high-thickness lipoprotein; LDL, low-density lipoprotein; SBP, systolic hypertension; T2D, type 2 diabetes.
A greater proportion of men than women was in the overweight range (BMI 25 to <30 kg/m 2 ), while women were more frequently in the obese range (BMI ?30 kg/m 2 ), in particular BMI 35 to <40 kg/m 2 . Smoking was more common among men than women (Table 1).There was an inverse relationship between age group and BMI, HbA1c, triglyceride, and DBP levels (Figure 1 stars: charts 2, 5, 8, and 10, respectively). Conversely, as age increased, the duration of T2D also increased, as did HDL-C and SBP levels (Figure 1 stars: charts 4, 6, and 9, respectively).
Bmi and you may cardio chance activities
Triglyceride, SBP, and DBP levels were directly correlated with BMI strata (Figure 1 triangles: charts 8–10, respectively). Conversely, as BMI increased, HDL-C levels decreased (Figure 1 triangles: chart 6); LDL-C levels did not show strong trends with BMI in either direction (Figure 1 triangles: chart 7). The generalized logit analysis confirmed positive associations between increasing BMI strata and SBP, DBP, and triglyceride levels as significant (P < .05 for all). It also indicated an inverse association between increasing BMI strata and HDL-C levels (P < .001) and a weaker inverse association between increasing BMI strata and LDL-C levels (P < .05).
There was an inverse relationship between BMI strata and both age and duration of T2D (Figure 1 triangles: charts 1 and 4, respectively). The generalized logit analysis confirmed these associations were significant (P < .001). HbA1c did not appear to be correlated with BMI strata (Figure 1 triangles: chart 5). 001).
HbA1c and cardiovascular exposure activities
Increased values for the cardiovascular risk factors LDL-C, triglycerides, SBP, and DBP, and decreased levels of HDL-C were related to higher HbA1c strata (Figure 1 circles: charts 7–10 and 6, respectively). In the generalized logit analysis, lower HDL-C (P < .001) and higher TC levels (P < .001) were associated with higher HbA1c strata. BMI and waist circumference did not show an association with HbA1c (Figure 1 circles: charts 2 and 3, respectively).